Leukemia pathology and Pediatricks MCQs Questions with Answers

Leukemia pathology and Pediatrics MCQs Questions with Answers

Question Part 1

1. What are the diseases related to systemic tumor diseases krovet Worn Fabric:

  • a) Leukemia
    b) Sarcoma
    c) Cancer
    d) Anemia
    e) Lymphoma

2. What group of tumors of the hematopoietic and lymphatic tissue does malignant lymphoma belong to?

a) Pretumor disease
b) Immune inflammation
+ c) Regional tumor disease of lymphoid tissue
d) Systemic tumor disease of hematopoietic tissue
e) Malignant tumor from the mesenchyme

3. What is called leukemias?

a) Regional tumor disease of hematopoietic tissue
b) Malignant tumor from the epithelium
+ c) Systemic tumor disease of hematopoietic tissue
d) Malignant tumor from the mesenchyme
e) Pretumor blood disease

4. What disease can be attributed to hemoblastosis?

a) Bone dysplasia
b) Retroperitoneal sarcoma
c) Lymphogranulomatosis
+ d) Acute leukemia
e) Kaposi’s sarcoma

5. Specify a synonym for the term leukemia:

a) Malignant lymphoma
+ b) Leukemia
c) Dysplasia
d) Sarcoma
e) Anemia

6. In what organs, systems of organs tumor cells grow in the initial stage of hemoblastosis?

  • a) In the bone marrow
    b) In the organs of the cardiovascular system
    c) In the musculoskeletal system
    d) In the organs of the respiratory system
    e) In the gastrointestinal tract

7. Specify the reasons for the sharp increase in organs in leukemia:

a) Formation of granulomas
b) Edema
c) Congestion
d) Sclerosis
+ e) Tumor cell metastases

8. Name the characteristic cytogenetic sign of chronic myeloid leukemia:

a) Absence of an autosome of the 13th pair of chromosomes
b) Intoxication with benzpyrene
+ c) The presence of the Philadelphia chromosome
d) Radiation
e) Viral infection

9. What leukemia is leukemic?

  • a) 100,000 leukocytes in 1 μl of blood
    b) 25,000 leukocytes in 1 μl of blood
    c) There are no leukemia cells in the blood
    d) The number of leukocytes in the blood is reduced
    e) In the blood “lupus” cells

10. What leukemia is called subleukemic?

a) 100,000 leukocytes in 1 μl of blood
+ b) 25,000 leukocytes in 1 μl of blood
c) There are no leukemia cells in the blood
d) The number of leukocytes in the blood is reduced
e) Rheumatoid factor in the blood

Question Part 2

 

11. What leukemia is called leukopenic?

a) 100,000 leukocytes in 1 μl of blood
b) 25,000 leukocytes in 1 μl of blood
c) There are no leukemia cells in the blood
+ d) The number of leukocytes in the blood is reduced
e) In the blood “lupus” cells

12. What leukemia is aleukemic?

a) 100,000 leukocytes in 1 μl of blood
b) 25,000 leukocytes in 1 μl of blood
+ c) There are no leukemia cells in the blood
d) Single leukemic cells in the blood
e) Rheumatoid factor in the blood

13. The analysis of the patient’s blood revealed 150,000 leukocytes in 1 µl of blood. What form of leukemia based on quantitative changes in blood should be considered?

a) Aleukemic leukemia
b) Subleukemic leukemia
c) Lymphogranulomatosis
d) Leukopenic
+ e) Leukemic leukemia

14. In analyzing the blood of the patient is detected 25 000 leucocytes in 1 ml of blood. What form of leukemia based on quantitative changes in blood should be considered?

a) Aleukemic leukemia
+ b) Subleukemic leukemia
c) Lymphogranulomatosis
d) Leukopenic leukemia
e) Leukemic leukemia

15. During the analysis of the patient’s blood, 2,500 leukocytes, and single leukemic cells were found in the blood. What form of leukemia based on quantitative changes in blood should be considered?

a) Aleukemic leukemia
b) Subleukemic leukemia
c) Kaposi’s sarcoma
+ d) Leukopenic leukemia
e) Leukemic leukemia

16. What are the principles of the modern classification of leukemia:

a) Duration of flow
+ b) The degree of differentiation of tumor cells and the nature of the course
+ c) Histo (cyto) genesis of leukemic cells
d) Features of the clinical course
+ e) Change in the number of leukocytes in the blood

17. What is the principle of dividing leukemia into acute and chronic:

a) Duration of flow
+ b) The degree of differentiation of tumor cells and the nature of the course
c) Histo (cyto) genesis of leukemic cells
d) The number of leukocytes in the peripheral blood
e) Localization of leukemic infiltrates

18. What disease is characterized by leukemic blood dip?

a) Lymphogranulomatosis
b) Pompe disease
+ c) Acute leukemia
d) Anemia
e) Lymphosarcoma

19. Name the history (cyto) genetic forms of chronic leukemia:

  • a) Lymphocytic
  • b) Monocytic
    c) Leukemic
  • d) Myelocytic
    e) Lymphoblastic

20. Name the forms of acute leukemia:

  • a) Megakaryoblastic
  • b) Lymphoblastic
    c) Multiple myeloma
  • d) Myeloblastic
    e) Myelocytic

Question Part 3

 

21. Name the forms of acute leukemia:

  • a) Undifferentiated
    b) Multiple myeloma
  • c) Monoblastic
    d) Lymphocytic
  • e) Erythromyeloblastic

22. Name chronic leukemia:

  • a) Multiple myeloma
    b) Lymphoblastic leukemia
  • c) Franklin Heavy Chain Disease
    d) Lymphosarcoma
    e) Undifferentiated leukemia

23. Name the leukemia of monocytic origin:

a) Lymphogranulomatosis
b) Lymphosarcoma
+ c) Histiocytosis
d) Myeloid leukemia
e) Erythromyelosis

24. Name the chronic lymphocytic leukemia:

  • a) Waldenstrom’s macroglobulinemia
  • b) Multiple myeloma
    c) Lymphoblastic
  • d) Skin lymphomatosis (Cesari’s disease)
    e) Lymphogranulomatosis

25. Name the history (cyto) genetic forms of chronic leukemia:

a) Leukemic
+ b) Erythremia
c) Myeloblastic
+ d) Lymphocytic
e) Leukopenic

26. What is the reason for the development of hemorrhagic syndrome in leukemias:

a) “Porphyry” spleen
b) Hyperplasia of the thymus
+ c) Leukemic infiltrates of the vessel walls
+ d) Thrombocytopenia
e) Hepatosplenomegaly

27. Specify the cause of anemia in leukemia:

a) “Porphyry” spleen
b) Avitaminosis B12.
+ c) Displacement of the red blood sprout
+ d) Bleeding
e) Leukemic infiltration of the vessel walls

28. What are the causes of death in acute leukemia:

  • a) Focal pneumonia
  • b) Necrotic ulcerative changes in the gastrointestinal tract
    c) Chronic venous plethora of internal organs
  • d) Brain hemorrhage
    e) Blast crisis

29. What are the main causes of death in chronic leukemia:

  • a) Secondary infection
  • b) Hemorrhage in the brain
  • c) Hepatic renal failure
  • d) Blast crisis
    e) Asystole

30. The study of the myelogram of a patient with acute leukemia showed a sharp increase in the number of blasts and single mature elements in the absence of transitional maturing forms. How to qualify for this change?

a) Myelosclerosis
b) Anemia
+ c) Leukemic failure
d) Bone marrow aplasia
e) Fatty metaplasia of the bone marrow

 

 

Question Part 4

 

31. What is the general pathological process that is the basis of the appearance of leukemic Institute leachate in organs?

a) Chronic venous congestion
b) Sclerosis
+ c) Metastasis
d) Displacement of a red sprout from the bone marrow
e) Portal hypertension

32. What complications occur in leukemias due to impaired immunity?

a) Hemorrhage in the brain
+ b) Sepsis, secondary infection
c) Acute adrenal insufficiency
d) Acute heart failure
+ e) Necrotic ulcerative changes in the gastrointestinal tract

33. What is found in the organs of hematopoiesis in acute leukemia?

a) Leukemic infiltrates from mature (citric) elements
b) Bone marrow sclerosis
c) Bone marrow hypoplasia
+ d) Leukemic infiltrates from blast cells
e) Metaplasia of bone marrow into bone tissue

34. What are the characteristic manifestations of acute leukemia in children:

  • a) Necrotic tonsillitis
  • b) Leukemic infiltration of the hematopoietic organs
    c) Chronic heart failure
    d) Acute renal failure
  • e) Leukemic infiltrates in organs

35. What form of acute leukemia is observed only in children?

  • a) Congenital leukemias
    b) Lymphocytic leukemias
    c) Paget’s disease
    d) Histiocytosis
    e) Cesari’s disease

36. Describe the type of bone marrow of long bones in patients with acute undifferentiated nym leukemias:

  • a) Red juicy
    b) Pyoid
    c) Yellow
    d) Obliteration of the bone marrow cavity
    e) Rusty

37. What are the common complications of acute leukemias:

  • a) Hemorrhagic syndrome
    b) Obesity
  • c) Attachment of a secondary infection
    d) Amyloidosis
  • e) Sepsis

38. Name the manifestations of acute leukemia:

a) Acute heart failure
b) Acute renal failure
+ c) Leukemic pneumonitis
d) Myocardial infarction
+ e) Leukemic meningitis

39. What are the stages of chronic myeloid leukemia:

  • a) Monoclonal
    b) Red dystrophy
  • c) Polyclinic
    d) Deployed changes
    e) Prodromal

40. Specify the macroscopic changes in organs in chronic leukemia:

a) Brown liver atrophy
+ b) Hepatomegaly
c) Heart hypertrophy
+ d) Splenomegaly
+ e) Swollen lymph nodes

Question Part 5

 

41. Specify a sign of exacerbation of chronic leukemias:

a) Thromboembolism of the pulmonary artery
+ b) Power crisis
c) Acute heart failure
d) Acute renal failure
e) Ascites

42. What cells appear in the blood at the terminal stage of chronic myeloid leukemia?

a) Myelocytes
b) Reticular
+ c) Myeloblasts
d) Berezovsky-Sternberg
e) Myeloma

43. Name the changes in the blood of a patient with chronic myeloid leukemia during exacerbation of the process:

  • a) Thrombocytopenia
    b) An increase in the number of mature white blood cells
    c) The appearance of reticulocytes
  • d) The appearance of blast forms
  • e) Anemia

44. Describe the type of bone marrow in a patient with chronic myeloid leukemia at autopsy:

a) Red, juicy
b) Rusty
c) Yellow bold
d) Yellow with red foci
+ e) Pyoid

45. Name the changes in the liver of patients with chronic myeloid leukemia:

  • a) Fatty degeneration of hepatocytes
  • b) Leukemic infiltrates along the sinusoids
    c) Leukemic infiltrates along the portal tracts
    d) Lipofuscinosis
    e) Hyperplasia of the bile ducts

46. ​​The patient has an enlarged liver and spleen. About 100,000 myelocytes were found in the blood. What leukemia should you think about?

a) Lymphoblastic
+ b) Myelocytic
c) Lymphocytic
d) Myeloblastic
e) Monocytic

47. The patient has an enlarged liver, spleen, all groups of lymph nodes. Blood zna considerably increases the number of lymphocytes. What disease should you think about?

a) Multiple myeloma
b) Lymphogranulomatosis
c) Acute myeloid leukemia
+ d) Chronic lymphocytic leukemia
e) Chronic myeloid leukemia

48. Name the changes in the liver of patients with chronic lymphocytic leukemia:

  • a) Leukemic infiltrates under the capsule
    b) Leukemic infiltrates along the sinusoids
  • c) Leukemic infiltrates along the portal tracts
  • d) Fatty degeneration of hepatocytes
    e) Leukemic infiltrates near the central vein

49. Describe the macroscopic view of the bone marrow in chronic leukemias:

a) Yellow
b) Red with yellow foci
+ c) Pyoid
d) With a rusty tint
e) Yellow with red foci

50. Name the typical manifestations of myeloma:

a) Pulmonary heart failure
+ b) Osteoporosis, paraproteinemia
+ c) Bens-Jones protein in the urine
d) Obesity
e) An increase in the number of leukocytes in the blood

Question Part 6

 

51. Name paraproteinemic leukemias:

  • a) Waldenstrom’s disease
  • b) Heavy chain disease
    c) Cesari’s disease
  • d) Multiple myeloma
    e) Myelocytic leukemias

52. What protein is produced by myeloma cells?

a) Alpha globulin
b) Albumin
c) Parathyroid hormone
+ d) Paraprotein
e) Serotonin

53. What leukemias are characterized by the presence of Bens-Jones protein in urine?

a) Myeloblastic
b) Myelocytic
+ c) Multiple myeloma
d) Lymphocytic
e) Megakaryoblastic

54. Name leukemia, a common complication of which is amyloidosis:

a) Lymphoblastic
+ b) Multiple myeloma
c) Myelocytic
d) Lymphosarcoma
e) Myeloblastic

55. To what leukemias according to quantitative changes in the blood does myeloma belong?

a) Leukemic
b) Subleukemic
c) Leukopenic
+ d) Aleukemic
e) Blast crisis

56. Indicate the biochemical essence of paraproteins:

a) Albumin
+ b) Pathological immunoglobulin
c) Glycosaminoglycans
d) Chondroitin sulfate
e) Porphyrin

57. What diseases belong to the group of chronic lymphocytic leukemias?

  • a) Franklin’s disease
    b) Paget’s disease
  • c) Waldenstrom’s disease
  • d) Rustitsky-Kalera disease
    e) Hodgkin’s disease

58. Name the most frequent localization of changes in the body in case of multiple myeloma:

a) Brain
+ b) Flat bones of the skull
+ c) Spine
d) Kidneys
e) Tubular bones

59. Specify a violation of mineral metabolism, is common in myeloma bolez not caused by osteoporosis:

a) Hypernatremia
b) Hyperphosphatemia
c) Hyperkalemia
+ d) Hypercalcemia
e) Hypocalcemia

60. List the causes of death of patients with multiple myeloma:

  • a) Focal pneumonia
    b) Ischemic cerebral infarction
    c) Myocardial infarction
    d) Cardiovascular failure
  • e) Renal failure

Question Part 7

 

61. What is the name of the spleen in lymphogranulomatosis?

a) Marble
+ b) Porphyry
c) Greasy
d) Variegated
e) Hyperplastic

62. Name the diseases related to lymphomas:

a) Cesari’s disease
b) Multiple myeloma
+ c) Lymphogranulomatosis
+ d) Brill-Simmers disease
e) Erythromyelosis

63. Name the stages (options) of lymphogranulomatosis:

a) Monoclonal
+ b) Depletion of lymphoid tissue
c) Polyclinic
+ d) With a predominance of lymphoid tissue
+ e) Modular sclerosis

64. Name the stages (options) of lymphogranulomatosis:

a) Monoclonal
+ b) With the suppression of lymphoid tissue
c) Polyclinic
+ d) Mixed-cell
e) Stage of scarring

65. Name non-Hodgkin lymphomas:

a) Lymphogranulomatosis
+ b) Burkitt’s lymphoma
+ c) Plasmacytoma
+ d) Fungal mycosis

66. Name the changes in the lymph nodes characteristic of the mixed cell variant of lymphogranulomatosis:

  • a) Growth of small and large Hodgkin cells
    b) Amyloidosis
  • c) Growth of Berezovsky-Sternberg cells
  • d) Necrosis
    e) Overgrowth of myeloma cells

67. What cells are of diagnostic value in lymphogranulomatosis?

  • a) Small and large Hodgkin cells
  • b) Giant cells of Berezovsky-Sternberg
    c) Myeloma cells
    d) Eosinophils
    e) Plasmablasts

68. Name malignant lymphomas:

  • a) Lymphogranulomatosis
    b) Multiple myeloma
  • c) Lymphocytic lymphoma
  • d) Brill-Simmers disease
    e) Erythromyelosis

69. In what organs are leukemic metastases most often preserved during treatment with cytostatic drugs?

  • a) Brain
    b) Heart
    c) Kidneys
    d) Pancreas
    e) Spleen

70. Name the form of acute leukemias in children with a favorable prognosis:

a) Monocytic
+ b) T-lymphoblastic
c) B-lymphoblastic
d) Myeloblastic
e) Undifferentiated

Question Part 8

 

71. Name the most common causes of death in lymphogranulomatosis:

a) Hemorrhages
+ b) Secondary infection
c) Bleeding
d) Osteoporosis
e) Necrotic nephrosis

72. Name the most common complications of lymphogranulomatosis:

  • a) Focal pneumonia
    b) Hemorrhage in the brain
  • c) Cachexia
    d) Myocardial infarction
    e) Ankylosis of the joints