Lymphogranulomatosis: Macro preparation and Micro preparation

Macro preparation and Micro preparation of Lymph node with lymphogranulomatosis

Describe the following macro and micro preparations of Lymphogranulomatosis

  • Description of the macro preparation:
    1. Which body or part thereof is represented
    2. Surface condition
    3. Sectional view
    4. The condition of the cavities
    5. The prevalence of the process
    6. Conclusion
  • Descriptionofthemicropreparation
    1. Which organ tissue is represented
    2. Structural changes
    3. The prevalence of the process
    4. Conclusion

 

Macro and Micro Preparations of lymphogranulomatosis

Macro and Micro Preparations of lymphogranulomatosis
lymphogranulomatosis

Description of the macro preparation:

  1. Lymph nodes of Neck
    • Peripheral lymph nodes generally – cervical, axillary, inguinal
  2. Surface condition
    • In the beginning –
      • Gray pink color of lymph node
      • Picture is erased
    • In Later –
      • Dry Lymph Node
      • Lymph node areas with necrosis and sclerosis
  3. Sectional view
    • Juicy lymph nodes
    • Dense lymph node
    • primary tumors (lymphomas)
    • fleshy mass
    • the involved lymph node is enlarged
    • Firm
  4. The condition of the cavities
    • Lungs – Centers of nodules have large vessels with lymphatic infiltration
    • Nodular Sclerosis
    • Swollen lymph nodes
  5. The prevalence of the process
    • The localization of primary lesions in the dentoalveolar system, oral cavity, organs, and tissues of the neck.
    • regional forms of cervical lymph node hyperplasia and their inflammatory lesions are more common than others in the presence of an infectious process in the oral cavity, dentoalveolar system
  6. Conclusion
    • The lymph nodes of both groups receive lymph from various areas of the head and neck and are often involved in pathological processes in the localization of primary lesions in the dentoalveolar system, oral cavity, organs, and tissues of the neck.

 

Description of the micro preparation of lympho-granulomatosis

  1. Which organ tissue is represented – Tends to spare lymphoid tissue
  2. Structural changes
    • indistinguishable, the cellular composition is polymorphic
    • Large Hodgkin and Reed-Sternberg cells are characteristic
    • vague nodules of small lymphocytes with sparse
    • relatively large tumor cells with multilobulated or round nucleus
    • thin nuclear membrane,
    • finely granular chromatin and variable small nucleoli (popcorn cells)
  3. The prevalence of the process
    • the predominance of lymphoid tissue
    • hyperplastic and inflammatory processes
    • Reactive hyperplastic lymphadenitis
    • In tuberculosis
  4. Conclusion
    • primary neoplastic processes (lymphomas) can develop in the cervical lymph nodes, as well as metastases of malignant tumors of other localization.