Acute pneumonia: Macro preparation and Micro preparation

Macro preparation and Micro preparation of Acute pneumonia (lobar, bronchopneumonia, interstitial or Hemorrhagic pneumonia)

Describe the following macro and micro preparations of Acute pneumonia

  • Description of the macro preparation:
    1. Which body or part thereof is represented
    2. Surface condition
    3. Sectional view
    4. The condition of the cavities
    5. The prevalence of the process
    6. Conclusion
  • Description of the micro preparation
    1. Which organ tissue is represented
    2. Structural changes
    3. The prevalence of the process
    4. Conclusion

 

Macro and Micro Preparations of Lobar pneumonia (Acute pneumonia)

Macro and Micro Preparations of Lobar pneumonia
Lobar pneumonia

Description of the macro preparation:

  1. In The lower lobe of Right Lung and Usually Unilateral
  2. The surface is rough and dry due to Fibrinous exudate on the pleura and the right lung was heavier than normal
  3. The parenchyma of the Right lower lung will mottled reddish grey.
  4. alveolar fluid rich and
  5. vascular engorgement and RBCs and neutrophils will less than normal in this condition
  6. The Pneumonia of the lung can diffuse consolidation in the entire lung (mainly the Lower Lobe of the right lung) and the Wall of the Alveoli will Thick due to edema and capillary congestion.

Description of the micro preparation:

  1. The parenchyma of the Right lower lung will mottled reddish grey.
  2. The alveolar lumen of the lungs, contains rarely leucocytes, serous exudates, and bacteria.
  3. It has stages that include Congestion, Red Hepatization, Grey Hepatization, and Resolution.
  4. Congestion of Alveoli will occur in this Pneumonia and the parenchyma will be damaged, and the lungs are getting Fibrous and water filled with the presence of Bacteria.

 

Macro and Micro Preparations of Hemorrhagic pneumonia (Acute pneumonia)

Macro and Micro Preparations of Hemorrhagic pneumonia
Hemorrhagic pneumonia

Description of the macro preparation:

  1. Also known as Diffuse alveolar hemorrhage (DAH)  in which bilateral pulmonary infiltrates are also present in the Bilateral lung, Mainly in all 5 lobes of the lungs.
  2. decreased integrity of the alveolar-capillary membrane
  3. hyaline membranes of diffuse alveolar damage
  4. The alveolar membrane will be damaged in patients
  5. Due to Soma bacteria, it can be developed and Most Common cause which includes connective tissue diseases and autoimmune diseases also.

Description of the micro preparation:

  1. hyaline membranes of diffuse alveolar damage
  2. Diffuse collagenous fibrosis, Organized thrombus, Endothelium Injury in Arteriole and Arteries. Thickening of pleura with dilatation of lymphatic/blood vessels
  3. Pneumonia with remnants of the hyaline membrane and the Proliferation of Intra alveolar space.
  4. Hemorrhagic Pneumonia shows that, damage of diffuse alveolar, which is Mainly identical to diffuse alveolar damage morphologically/acute respiratory distress syndrome. In this situation, the fibrotic (chronic) phase and exudative (acute) phase can happen.

 

Macro and Micro Preparations of Broncho-pneumonia (Acute pneumonia)

Macro and Micro Preparations of Broncho-pneumonia
Broncho-pneumonia

Description of the macro preparation:

  1. in diameter throughout both lower lobes.
  2. No pleural exudate and nodular, firm, reddish grey areas of 1 cm.
  3. fluid could be expressed
  4. homogenous edema (pale pink) fluid in the alveoli
  5. Mainly caused by bacteria. Patchy consolidation of peribronchial lung tissue. Then due to swollen mucosa and their secretion, the bronchial plugged forming there.
  6. This is a type in which inflammation can occur in the lungs (in alveoli and alveolar sacs). Then it causes difficulty in breathing due to inflammation in the alveolar sacs.

Description of the micro preparation:

  1. Parenchymal destruction
  2. Bronchocentric lesion, Consolidation of Peribronchial lung alveoli
  3. patchy exudative consolidation
  4. terminal bronchiolitis with consolidation of peribronchial alveoli